Welcome to the website of InSight Pathology !
InSight Pathology is a privately owned company located in the South-East of the Netherlands, offering services related to toxicologic pathology. With more than 25 years of experience in the pharmaceutical industry and around 10 years of experience in the consultancy business as an independent board certified toxicologic pathologist, a broad range of challenges in toxicologic pathology have been addressed and have strengthened my knowledge, experience, capability and insight.
Straightforward studies and interpretations of toxicology issues rarely exist, and bespoke solutions are often required. It is therefore a benefit to realize that InSight Pathology has the expertise to support you with these studies, by slide reading and independent peer reviews on the one hand, and consultancy on the other.
We welcome you to contact InSight Pathology should you have further questions after having read through this website. We are confident that there is a way in which we can help you with the questions you have and issues or challenges that you face.
Regards
Eric van Esch
BY DISSECTING A PATHOLOGIST'S BRAIN, ULTIMATELY, WHAT YOU FIND IS A DEDICATED HEART
Gianni Bussolati
InSight Pathology offers more than 3 decades of experience within toxicologic pathology. This experience is translated to the following services:
MICROSCOPIC SLIDE EVALUATION
InSight Pathology can perform slide reading for your non-clinical safety studies and perform the overall interpretation of findings in these studies. Slide reading for GLP as well as non-GLP studies can be performed. InSight Pathology uses the PathData System for entry and evaluation of pathology data resulting from toxicity and carcinogenicity studies, but also can work on remote systems of test facilities. InSight Pathology has experience in a broad range of studies, varying from short term to carcinogenicity studies, and from studies in rodents (including transgenic animals) to studies in minipigs and non-human primates, using different routes of administration. In addition, many different pharmaceuticals (including biologicals) from a wide range of therapeutic areas as well as different type of chemicals have been assessed for their safety.
INDEPENDENT PEER-REVIEW
Besides primary slide reading for your studies, InSight Pathology can also perform the independent peer-review process for your non-clinical safety studies, when necessary under GLP. Pathology peer review can help to ensure the quality and accuracy of histopathological diagnoses, correct use of terminology (according to INHAND - International Harmonization of Nomenclature and Diagnostic Criteria) and scientific interpretations.
CONSULTANCY
InSight Pathology can provide you with advice on all issues related to toxicologic pathology. To be able to give valuable advice, experience is key. With almost 30 years of experience a broad range of challenges in toxicologic pathology have been faced and have strengthened the knowledge, experience, capabilities and insight. With this background, InSight Pathology is confident to be able to advise on the way forward for your project (when pathology is concerned), to advise on follow up activities when certain findings are difficult to interpret or make an overall interpretation of pathology findings over different studies. InSight Pathology can also support you in your Due Diligence preparation when an in-depth evaluation of the toxicologic pathology part is needed.
Please contact InSight Pathology for more information, or when you want to request a quotation for one of your studies (slide reading or peer-review) or for consultancy activities.
THINK WITH THE EYES AND SEE WITH THE BRAIN
Daniel Mazia
For good interpretation of pathology findings experience is key. To give an idea of the experience of Eric van Esch, you are free to request his full Curriculum Vitae at eric.vanesch@insightpathology.com. Of special note here are the several Pathology Working Group (PWG) meetings that Eric has participated in over the last years and for which he was asked to participate based on his broad knowledge and experience.
A list of studies/projects he was involved in as principal investigator (study pathologist), as peer-reviewing pathologist or as consultant during the nearly 10 years he worked for his own company is also available upon request.
VISION IS THE ART OF SEEING WHAT IS
INVISIBLE TO OTHERS
Jonathan Swift
Testimonials
THERE IS ONLY ONE WAY TO SEE THINGS, UNTIL SOMEONE SHOWS US HOW TO LOOK AT THEM WITH DIFFERENT EYES
Pablo Picasso
In April 2019 InSight Pathology successfully passed the inspection by the Dutch authorities (IGZ) for compliance to the principles of OECD GLP, for the fourth time.
GLP Accreditation
THE ONLY SOURCE OF KNOWLEDGE IS EXPERIENCE
Albert Einstein
Contact
Eric van Esch
InSight Pathology BV
Chopinlaan 6
5343EM Oss
The Netherlands
Usefull links
For nonclinical consultancy (i.e. services related to all aspects of nonclinical development; from writing a drug development plan, to supporting companies in meetings with regulatory authorities, and ‘everything in between’) I recommend to contact Ilonka van Hoof at NonClinical Insights:
Ilonka van Hoof
+31 6 27247093
